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Terms with an adjusted P 1 of the RRM2 gene in the PTC tissues was used as the cut-off point for the expression level to classify the samples into the high-expression group and the low-expression group, and further analyses showed that, as shown in Supplementary Table 2 , we found that the RRM2 expression level was correlated with tumor size (P = 0.0048), which may indicate that RRM2 acts as a potential oncogenic factor in PTC

After washing with DMSO and Milli-Q (Millipore, Billerica, MA, USA) water, the tips were incubated with 10 L of a 10 M solution of p29 in 50 mM phosphate buffered saline (PBS), pH 7.5, overnight at 4C

Epidemiol Rev, 2001, 23:72-81

Natural production within the body declines with age, and most supplements are not stable enough to be effective