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In a randomized, placebo-controlled trial involving 121 subjects with ulcerative colitis, propionyl-L-carnitine , at 1 or 2 grams daily, led to greater remission rates than placebo when added to conventional therapy (Mikhailova 2011)

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Conclusively, these data reveal the acute immune attacks by macrophages and T cells during relapses, whereas chronic progression of the disease is associated with B cell infiltration