The effects typically last for several days to weeks, depending on individual needs and lifestyle
The largest dataset based on whole-body counting is provided by Heinrich (Heinrich, 1967), who studied doses up to 100,000 g
Stimulants, including amphetamine, methamphetamine, cocaine, and ephedrine exceeding regulatory thresholds, are banned in competition due to their alertness-promoting and fatigue-masking properties
One example is vitamin D, which experienced a rapid surge and widespread hype in the 2000s, followed by a period of conflicting headlines and public skepticism, before a stronger evidence base emerged to establish its benefits and safety. NAD+ appears to be following a similar trajectory of early excitement, some overstated fears, and, now, a growing body of research helping provide more insight into its benefits