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While GLP-1 medications offer potential health benefits, their long-term effects remain an area of active study

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Initial studies had indicated DPP-4 to be an adipokine due to its release from the adipocyte membrane through the action of matrix metallopeptidase 9 (MMP9), resulting in the release of the soluble DPP-4 form in the circulation [35]

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Yadlapati S, Snchez-Luna SA, Gromski MA, Mulki R

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Many of these men will not discuss these issues with their care providers out of embarrassment, a sense of helplessness or fear of unknown treatments

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