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It provides a model for investigating how a simple molecule can act as a master regulator, influencing multiple interconnected pathways to shift the overall state of a cell or tissue culture

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Experimental approaches include behavioral testing (Morris water maze, novel object recognition), electrophysiology (LTP recording), neurochemical analysis, imaging techniques (PET, MRI), and various neurotoxin or transgenic disease models

Patients with type 2 diabetes, following postprandial hyperglycemia (rapid increase in blood levels of glucose) exhibit significantly increased oxidative stress markers (Ceriello et al