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This is mechanistically demonstrated in breast cancer models, where SFN, by activating the Nrf2 pathway, reduces the secretion of prostaglandin E2 (PGE2) from tumor cells, thereby triggering MDSCs to switch from an immunosuppressive to an immunogenic phenotype and inhibiting their expansion (76)

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Like astaxanthin, lutein and zeaxanthin are fat-soluble compounds, meaning absorption is improved when they are delivered alongside dietary fat.16 The medication format really matters, says Dr